A comprehensive Japanese genetic variation database

2021/12/16

• Datasets: ToMMo 4.7KJPN was updated to ToMMo 8.3KJPN (ToMMo 8.3KJPN Allele Frequency Panel).
• Datasets: ExAC was updated to gnomAD v2.1.1 (The Genome Aggregation Database).

2020/10/22

• Keyword search: You can search TogoVar by Human Genome Variation Society (HGVS) description(e.g.ALDH2:c.1510G>A or ALDH2:p.Glu504Lys).

2020/7/27

• Datasets: The new dataset, GEM-Japan Whole Genome Aggregation (GEM-J WGA), was added. Additionally, ToMMo 3.5KJPN was updated to ToMMo 4.7KJPN (ToMMo 4.7KJPN Allele Frequency Panel). ClinVar information was also updated.
• Usability: You can search the variants on Karyotype image.

2019/7/25

• Keyword search: You can search TogoVar by an alias name of HGNC Gene Symbol (e.g. PD-1, p53).
• Filters: You can specify either all or any of datasets of your choice as a target when searching by an alternative allele frequency.
• Filters: You can filter variants by Consequence value, SIFT and/or Polyphen score.
• Filters: You can hide and show low quality variants.
• Datasets: ToMMo 3.5KJPN was updated to Ver.2 (ToMMo 3.5KJPNv2 Allele Frequency Panel). ClinVar, Variant Effect Predictor (VEP) and Ensembl were updated as well. See Datasets for detail.
• Usability: You can choose the data items to display at the Configuration menu.
• Usability: The user interface was refined for easier use.

2018/6/7

• TogoVar has been released. See a EurekAlert! press release for detail.